Primary Renal Synovial Sarcoma: A Rare Oncologic Mimicry

Primary Renal Synovial Sarcoma: A Rare Oncologic Mimicry
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Title:Primary Renal Synovial Sarcoma: A Rare Oncologic Mimicry
Author/Abstract:

Jay-R R. Enojo, MD; Ernesto L. Gerial Jr., MD, FPUA and Hyacinth Joy A. Balderama
Department of Urology, National Kidney and Transplant Institute

Primary renal synovial sarcoma is a rare condition. Early diagnosis is difficult because it mimics the
features of other common renal tumors. There are less than 70 cases reported internationally to date
and the first locally. Herein, we describe a case of a 64 year old female, diagnosed case of renal cell
carcinoma and underwent laparoscopic radical nephrectomy. Final histopathology however revealed
a primary renal synovial sarcoma, confirmed by immunohistochemistry and flourescence in situ 
hybridization. There are no established treatment guidelines for this condition due to the limited
number of cases reported. The role of adjuvant chemotherapy is controversial and unclear.

Key words: Primary renal synovial sarcoma, immunohistochemistry, fluorescence in situ
hybridization, adjuvant chemotherapy

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