An Orbital Metastasis of Prostate Adenocarcinoma: A Rare Case Report

An Orbital Metastasis of Prostate Adenocarcinoma: A Rare Case Report
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Title:An Orbital Metastasis of Prostate Adenocarcinoma: A Rare Case Report
Author/Abstract:

Rogelio F. Varela Jr., MD1; Joseph Ursua, MD1; Jaime C. Balingit, MD, FPUA1;Lawrence Joseph S. Valdez, MD2; Gloria Lim, MD2

1Department of Urology, East Avenue Medical Center
2Department of Health, Eye Center, East Avenue Medical Center

A patient with known prostatic cancer presented with left supraorbital swelling with proptosis
and restricted eye movements on left eye. Contrast enhanced computed tomography scan revealed
dural and bone metastases with soft tissue component extending to the left orbit. Serum prostate
specific antigen was markedly elevated at >100 ng/ml. Incision biopsy of the orbital tumor revealed
only lymphocytic inflammatory cells within the fibrous stroma attributed mainly to the deeper location of the tumor or shallow locus of the biopsy. Incisional biopsy of the frontal bone revealed atypical looking cells in sheet cluster with nuclear enlargement, hyperchromatic in irregularity confirming the diagnosis of orbital metastasis of prostate carcinoma.

Metastasis of prostate cancer to the orbit is rare. One should have a high index of suspicion of
orbital metastasis when presented with an elderly patient with ocular symptoms and a history of
prostate adenocarcinoma. A thorough clinical, radiological and histological evaluation is necessary
to establish the diagnosis.

Key words: Orbital metastasis, ocular metastasis, prostate adenocarcinoma

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