Data Support Intermittent ADT for Metastatic PCa

Intermittent androgen deprivation therapy (ADT) may be as safe as continuous ADT in the treatment of metastatic prostate cancer (PCa), researchers concluded....

Stereotactic Radiosurgery Promising for Renal Cancer

The modality may provide a safe noninvasive treatment option....

Metabolic Abnormalities Following Urinary Diversion

Metabolic Abnormalities Following Urinary Diversion Radical cystectomy with urinary diversion including neobladder remains the standard of care for muscle-invasive bladder cancer....

Protection Against Bladder Cancer Offered By High Levels Of Vitamin D In Plasma

email icon High levels of vitamin D are associated with protection against bladder cancer, according to a multidisciplinary study coordinated by molecular biologists and epidemiologists from the Spanish...

Nonmuscle Invasive Bladder 
Cancer: Guidelines for Treatment

The routine incorporation of NMIBC clinical practice guidelines will reduce variation in care by closing the gap on inappropriate delivery, whether over- or underuse....

Cancer Survivors Report Lower Quality of Life (CME/CE)

Cancer Survivors Report Lower Quality of Life (CME/CE) (MedPage Today) -- Cancer survivors may be cured of their disease, but they are still more likely to report a poorer quality of physical and mental health than adults who have not had cancer,...

Diabetes Surgery Tops Medical Innovation List

(MedPage Today) -- Bariatric surgery for diabetes treatment was selected as the most important medical innovation for 2013 in a poll of Cleveland Clinic physicians and researchers....

Annual PSA Screening May Benefit Some Men

Greater quality-adjusted life expectancy found for men at high risk for metastatic disease....

SBRT Promising for Intermediate-Risk PCa

Stereotactic body radiotherapy is associated with a 99% four-year progression-free survival rate....

Robotic Partial Nephrectomy Advance Reported

A new type of robotic-assisted surgery is streamlining partial nephrectomy....

Quality Of Life For Men With Prostate Cancer Preserved By Proton Therapy Treatment

email icon Two studies led by The University of Texas MD Anderson Cancer Center have found that proton therapy preserves the quality of life, specifically urinary and bowel function, in men treated with this...

Why Antibiotics Prescribed For Chemotherapy Cause Kidney Failure

email icon Neutron scattering experiments have provided new insights into the origin of the side effects of an antifungal drug prescribed all over the world. The analysis conducted by scientists at King's...

High levels of vitamin D in plasma protects against bladder cancer

High levels of vitamin D are associated with protection against bladder cancer, according to a study by molecular biologists and epidemiologists....High levels of vitamin D in plasma protects against bladder cancer

UTI Reports to CDC May Be Misleading

Discrepancies found in competing definitions of catheter-related urinary tract infections...

Prostate Cancer Patients Find It Difficult To Understand Websites

email icon Ninety million adults in the U.S. do not read at levels higher than high school, therefore, the NIH (National Institutes of Health) is suggesting that patient information material should be written...

Radium-223 Extends Survival in CRPC (CME/CE)

Radium-223 Extends Survival in CRPC (CME/CE) BOSTON (MedPage Today) -- Men with metastatic castration-resistant prostate cancer lived significantly longer when treated with a bone-targeted, alpha-emitting agent, a randomized trial showed....

Prostate cancer prognosis hope

Scientists have discovered a molecular ‘tell’ in laboratory experiments that could help doctors determine the severity of a patient’s prostate cancer....Prostate cancer prognosis hope

New Nano Drug Delivery System Developed For Bladder Cancer

email icon A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy...

Patients Report Better Early QOL with Proton Therapy

Proton therapy was associated with less urinary and bowel dysfunction than 3D-CRT and IMRT in the first few months following treatment....

Testosterone Deficiency To Have Big Public Health Impact

Researchers predict about 1.3 million new cases of cardiovascular disease related to low testosterone over a 20-year period....

Robotic Cystectomy May Be Better Option for Elderly Patients

Study findings lower rate of early complications compared with younger patients undergoing open surgery....

Which do you think is better for preoperative male genital hair removal?

A recent study published in the Journal of Sexual Medicine tested which is the better way to perform preoperative genital hair removal on men....

Hydration Based On Ventricular Pressure Is Effective In Reducing Kidney Damage In Patients Undergoing Cardiac Catheterization

email icon Results of the POSEIDON trial presented at TCT 2012 A hydration regimen tailored to the patient's fluid status was effective in reducing damage to kidneys in patients undergoing cardiac...

Slings Effective for Male SUI

Surgical placement of male transobturator slings cures three-quarters of cases of male stress urinary incontinence (SUI) that develop as a result of prostate surgery....

4 New Clinical Practice Guidelines Issued By The American Urological Association

email icon The American Urological Association (AUA) introduces new clinical guidelines for the treatment of Overactive Bladder, Urodynamics, Hematuria, and Vasectomy......

Preventive Guidelines For Catheter-Associated Urinary Tract Infection Not Followed In Many Intensive Care Units

email icon Hospital size matters when it comes to intensive care units (ICUs) adopting even the most routine prevention policies for catheter-associated urinary tract infections (CAUTI), according to a new...

New clinical practice guidelines for overactive bladder, urodynamics, hematuria, and vasectomy

The American Urological Association introduces new clinical guidelines for the treatment of overactive bladder, urodynamics, hematuria, and vasectomy. The guidelines, which were developed using a...

Costs Significantly Less When Outpatient Urological Surgery Performed In Physician Offices ACCs

email icon More and more outpatient surgical procedures are being done at nonhospital-based facilities such as freestanding ambulatory surgical centers and physician offices, instead of at hospital-based...

Promising new biomarker for aggressiveness of prostate cancer

Researchers have found increased levels of serum glutamate in both primary and metastatic prostate tumors, corresponding to increasing Gleason score....Promising new biomarker for aggressiveness of prostate cancer

Noninvasive assay monitored treatment response in patients with metastatic prostate cancer

Deciding the ideal treatment for patients with metastatic prostate cancer that stops responding to initial therapy could be guided by certain analyses of cancer cells isolated from the patients'...

TCT: Stents Help Some Erectile Dysfunction (CME/CE)

TCT: Stents Help Some Erectile Dysfunction (CME/CE) MIAMI (MedPage Today) -- Stenting blocked arteries in the pelvis may improve sexual function for certain men with erectile dysfunction unresponsive to medical therapy, longer-term follow-up of a...

Older Men's Sperm Benefit from Micronutrients

A new study suggests that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older men....

Study: Percutaneous Renal Biopsies Safe

Researchers in Norway demonstrate a less than 1% overall rate of complications....

Metabolic factors may increase men's risk of dying from prostate cancer

High blood pressure, blood sugar, blood lipids, and body mass index-characteristics that are often lumped together as the metabolic syndrome-are jointly linked with an increased risk of dying from...

Catheter-Related UTIs Not More Frequent in the ICU

Catheter-associated urinary tract infections (CAUTIs) occur at similar rates in the intensive care unit (ICU) and in non-ICU settings....

Engineered 'Organoids' Function Like Real Kidneys When Implanted Into Rats

email icon With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another...

Prostate Cancer Death Risk Raised By Metabolic Factors

email icon A man's chances of dying from prostate cancer are higher if he has a high BMI (body mass index), hypertension (high blood pressure), and raised blood sugar and/or blood lipids, which collectively...

New Target For Treating Diabetic Kidney Disease, The Leading Cause Of Kidney Failure

email icon About 20%-30% of patients with diabetes develop evidence of diabetic nephropathy. Researchers have discovered a new therapeutic target for diabetic nephropathy, the leading cause of kidney failure....

Kidney Failure Patients' Heart Risks May Be Due To Damage To Blood Vessel Lining

email icon Individuals with kidney failure often develop heart problems, but it's not clear why......

BMI, BP Don't Up Prostate Cancer Risk (CME/CE)

BMI, BP Don't Up Prostate Cancer Risk (CME/CE) (MedPage Today) -- Metabolic factors did not increase the risk of prostate cancer but modestly raised the risk of prostate cancer mortality, results of a large cohort study showed....

Mesh Sling Salvage Surgery Results Mixed

Even if salvage operations ease complications from unsuccessful mesh sling surgery, patients often are in worse condition than before their original surgery....

Horizontal Loops in Catheter Tubing Make for Worst Flow

Horizontal loops in catheter tubing can reduce flow rate by nearly two-thirds....

For Small Kidney Masses, Active Surveillance Provides A Viable Alternative To Surgery

email icon Active surveillance of small kidney masses is a safe and effective alternative to immediate surgery, with similar overall and cancer specific survival rates, according to a study published in the...

Cranberry Juice Ineffective Against Cystitis, Bladder Infections

email icon Cranberry extract does not prevent urinary tract infections (UTI) and bladder infections, such as cystitis, while any slight advantage would only be seen in women with recurrent UTIs. This is the...

Bladder Cancer Mortality Increased By Depression And Shortened Telomeres

email icon The combination of shortened telomeres, a biological marker of aging associated with cancer development, and elevated depression significantly impacted bladder cancer mortality, according to data...

Risk For Bladder Cancer Increased By 2 Components Of Red Meat Combined With Alteration In DNA Repair

email icon Two components of red meat - dietary protein and dietary iron - may combine to form powerful carcinogens, N-nitroso compounds, which increase risk for bladder cancer. Moreover, individuals with...

Postop Radiation Slows PSA Rise in High-Risk Prostate Cancer (CME/CE)

Postop Radiation Slows PSA Rise in High-Risk Prostate Cancer (CME/CE) (MedPage Today) -- Men with high-risk prostate cancer had a significantly lower risk of biochemical relapse when treated with adjuvant radiation therapy after radical prostatectomy, results of a...

Green tea reduced inflammation, may inhibit prostate cancer tumor growth, research finds

Men with prostate cancer who consumed green tea prior to undergoing prostatectomy had reductions in markers of inflammation, according to new data...Green tea reduced inflammation, may inhibit prostate cancer tumor growth, research finds

Urine Stream Shape May Help Diagnose Prostate Problems

email icon New research from the UK suggests that the shape of a man's urine stream may help diagnose prostate and urinary problems. The researchers hope their findings will lead to a solution that helps...

Urinary Tract Infections Unlikely To Be Prevented By Cranberry Juice

email icon Cranberry juice is unlikely to prevent bladder and kidney infections, according to an updated systematic review published in The Cochrane Library. The authors analysed the most up-to-date evidence...

Improving Outpatient Management Could Reduce The High Rate Of Readmission Of Kidney Transplant Patients

email icon Three in 10 patients receiving a kidney transplant require readmission to the hospital within 30 days of discharge following surgery, according to a Johns Hopkins analysis of six years of national...

Increased flavonoid intake reduced risk for aggressive prostate cancer

A high total intake of flavonoids, a group of compounds found in plants, was inversely associated with the risk for highly aggressive prostate cancer, according to new data....Increased flavonoid intake reduced risk for aggressive prostate cancer

Cranberries of Little Help in Preventing UTI (CME/CE)

Cranberries of Little Help in Preventing UTI (CME/CE) (MedPage Today) -- Cranberry products were no more effective at preventing urinary tract infections than a range of other treatments in most populations, a systematic review found....

Shape of urine can indicate prostate issues: Characteristic shape of a man's urine can help diagnose urinary problems

Scientists have discovered a simple test which uses the biomechanics of the shape of urine to help diagnose urinary problems....Shape of urine can indicate prostate issues: Characteristic shape of a man's urine can help diagnose urinary problems

Stat5 predicts outcomes for prostate cancer patients after radical prostatectomy

Men who had high levels of the activated Stat5 protein in their prostate cancer after a radical prostatectomy were more likely to have a recurrence or die from the disease compared to men who had...

News From The Journal Of Clinical Investigation: Oct. 15, 2012

email icon Hypertension: It's all in your head Hypertension affects nearly 1 billion people worldwide and increases the risk for diseases of the heart, kidney, and brain. Endoplasmic reticulum (ER) stress in...

Bladder Regeneration Discovered In Mammal Model

email icon While it is well known that starfish, zebrafish and salamanders can re-grow damaged limbs, scientists understand very little about the regenerative capabilities of mammals. Now, researchers at Wake...

For Low-Risk Prostate Cancer, Surgery Or Radiation, Not Monitoring, Most Often Sought

email icon Few physicians recommend active surveillance for low-risk prostate cancer rather than pursuing surgery or radiation, according to a Mayo Clinic study presented at the North Central Section of the...

Gene Signature Predicts Worse PCa Patient Survival

Survival times were 7.8 months in men with the signature, 34.9 months in those without it....

Identification of stem cells that contribute to prostate development

Researchers have identified multipotent and unipotent stem cells (SCs) that contribute to prostate postnatal development....Identification of stem cells that contribute to prostate development

Lab Notes: Itchy Mice Stop Scratching

(MedPage Today) -- A solution for eczema may lie in blocking the response that causes the inflammation. Also this week, curry to help fight cancer and growing new capillaries below the knees....

HoLEP An Option After Failed Prior BPH Surgery

Study reveals no significant difference in operative or postoperative complications in patients with and without prior surgery....

HoLEP An Option After Failed Prior BPH Surgery

Study reveals no significant difference in operative or postoperative complications in patients with and without prior surgery....

Prostate Cancer: Genes Predict Survival (CME/CE)

Prostate Cancer: Genes Predict Survival (CME/CE) (MedPage Today) -- Two different genetic signatures may offer some clue about prognosis in castration-resistant prostate cancer....

Gene signature predicts prostate cancer survival

Researchers have identified a six-gene signature that can be used in a test to predict survival in men with aggressive prostate cancer....Gene signature predicts prostate cancer survival

Larger Stones Increase Post-SWL Steinstrasse Risk in Children

Steinstrasse developed in 7.6% of cases, and in most instances was successfully managed with repeat SWL....

Skin-to-Stone Distance Useful In Predicting ESWL Success

Shorter distances are associated with higher stone-free rates....

Marathon runners may be at risk for incontinence

While many marathon runners may be preoccupied with shin splints, chafing and blisters come race day, one thing they may not consider is their bladder health....Marathon runners may be at risk for incontinence

Botox as Good as Anticholinergics for Incontinence (CME/CE)

Botox as Good as Anticholinergics for Incontinence (CME/CE) (MedPage Today) -- In a head-to-head trial, two therapies for idiopathic urgency urinary incontinence had equivalent results, researchers reported....

Botox versus oral medication for women's incontinence: Benefits, drawbacks described

Oral medication for treating a type of incontinence in women is roughly as effective as Botox injections to the bladder, reported researchers who conducted a clinical trials network study, with each...

Revlimid Combo Fails as Prostate Cancer Therapy

Revlimid Combo Fails as Prostate Cancer Therapy VIENNA (MedPage Today) -- Adding lenalidomide (Revlimid) to other chemotherapy led to greater toxicity and worse survival in patients with untreated castration-resistant prostate cancer, results of...

Novel Drug Shows Activity in Prostate Cancer

Novel Drug Shows Activity in Prostate Cancer VIENNA (MedPage Today) -- An investigational androgen receptor antagonist achieved partial response or stable disease after 12 weeks of therapy in almost all evaluable patients with...

PSA Testing Boosts Survival in African-American Men

The routine use of PSA testing for screening and monitoring prostate cancer has led to earlier and more sensitive detection of the disease....

PSA Testing Boosts Survival in African-American Men

The routine use of PSA testing for screening and monitoring prostate cancer has led to earlier and more sensitive detection of the disease....

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